Mark Eisner, MD


  • Accepting new patients
About Mark Eisner, MD

Married with three children, Dr. Eisner was born in Manhattan and raised in New Rochelle, NY. He is head of the Department of Gastroenterology for Florida Medical Clinic Orlando Health and also serves on the Florida Medical Clinic Orlando Health Board of Directors. Dr. Eisner also serves as the Endoscopy Medical Director at the Zephyrhills Special Procedures Surgery Center. When he is not working, Dr. Eisner enjoys spending time with his family. He enjoys traveling, golfing, and collecting stamps, a life-long hobby.

Board Certifications
  • American Board of Internal Medicine
  • Internal Medicine
  • Gastroenterology
Medical Education

The George Washington School of Medicine
Washington, D.C.


Francis Scott Key Medical Center
Baltimore, MD


Georgetown University Medical Center

Hospital Memberships

AdventHealth Zephyrhills
FMC Special Procedures Center, Zephyrhills
FMC Ambulatory Surgery Center, Tampa
AdventHealth Dade City

Special Interests

Gastroesophageal Reflux Disease
Hepatitis C
Colorectal Cancer

Zephyrhills 38135 Market Square Drive Zephyrhills, Florida 33542  Suite 101


38135 Market Square Drive
Zephyrhills, FL 33542

Suite 101

P: (813) 780-7534
F: (813) 355-5033
Provider Hours
  • Monday: 7am - 4pm
  • Tuesday: 7am - 4pm
  • Wednesday: 7am - 4pm
  • Thursday: 7am - 4pm
  • Friday: 7am - 12pm

Florida Medical Clinic Orlando Health participates with most major carriers. Please consult your insurance carrier prior to your appointment to verify our participation status with your insurance plan. This list is subject to change and is not all-inclusive.

  • Aetna HMO
  • Aetna Medicare HMO
  • Aetna Medicare PPO
  • Aetna PPO
Allwell by Sunshine (Medicare HMO)
  • AvMed HMO
  • AvMed PPO
Blue Cross Blue Shield aka: Florida Blue
  • BC Advantage 65
  • BCBS Medicare HMO
  • BCBS Medicare PPO
  • BCBS PPO (Includes EPO, PPC, BlueOptions, Blue Select)
  • CarePlus Medicare HMO
Cigna (Includes Great West)
  • Cigna HMO
  • Cigna PPO
  • Coventry HMO
  • Coventry Medicare HMO
  • Coventry Medicare PPO
  • Coventry PPO
Freedom Health Medicare Advantage Plan HMO
Health First Health Plans
  • Humana HMO
  • Humana Medicare HMO (including Gold Plus HMO)
  • Humana Medicare PPO (Includes Choice PPO/PFFS)
  • Humana PPO
Longevity Health Plan
Multiplan (Includes Multiplan, Beechstreet/ PHCS)
Partners Direct Health (includes Hendry Marine Industries, ABC Fine Wine & Spirits, & Trustmark- Word of Life)
Railroad Medicare
  • Tricare East
  • Tricare East HMO (Prime)
United Health Care
  • United Healthcare AARP Medicare Complete HMO
  • United Healthcare AARP Medicare Complete PPO
  • United Healthcare Dual Complete HMO
  • United Healthcare Dual Complete PPO
  • United Healthcare HMO
  • United Healthcare PPO
Wellcare by Allwell (Medicare Advantage HMO Plan)
  • Wellmed- UnitedHealthcare Medicare


"Dynamic, well orchestrated symphony of caring service professionals!"

I am SO happy that I found Dr Mark Eisner and had the opportunity to seek treatment under his direction at the Florida Medical Clinic Orlando Health Zephyrhills location. It can be an intimidating experience to have not one, not two, but three procedures performed within a 6 week period. But, I will attest, with conviction, that I NEVER felt uncomfortable, nervous, scared or apprehensive. And THAT says a lot! In addition to the premier medical care Dr Eisner provided, I MUST commend the staff, or should I say, the team that so masterfully attended to my every need. This team consisted of Charlotte, Samantha, Lauren and Abby. They are a dynamic, well orchestrated symphony of caring service professionals! Kudos and a HUGE Thank YOU! I am VERY impressed with the stellar level of care, continuity and compassion I received as a patient at Florida Medical Clinic Orlando Health.... Read More +
John B.

"I felt at ease with his tone, demeanor & willingness to listen"

I contacted Dr. Eisner for a second opinion before making a decision on colon surgery. Immediately, I felt at ease with his tone, demeanor and willingness to listen and put me at ease. Keep in mind that this was a first appointment and it was a tele-med appointment. Looking forward to my in-person appointment next month.
James M.

"Very dedicated to helping his patients"

I'm very satisfied and happy with the care I have, and am receiving! Dr. Eisner is a very caring person, and seems very dedicated to helping his patients.

"Very caring & exceptional."

Dr Eisner & his associates and staff are very caring and exceptional.

"Best doctor in the town"

Dr. Eisner is the best doctor in the town. He has provided the best guidance and service. He is my doctor at least for the last 15 years.

"Goes above and beyond"

Dr. Eisner is a terrific doctor that actually genuinely cares about his patients. He goes above and beyond to make sure you are properly diagnosed, takes his time explaining any concerns and always checks to see if you have any questions for him. I never feel rushed by him. Dr. Eisner and his staff have always been kind and compassionate.

"Always puts a smile on your face"

Dr. Eisner and his staff are awesome! Everyone at that office including Dr Eisner are always very accommodating! If I need something, someone's always there to answer my question. I'm just very happy with the overall service! I usually hate going to the doctor's, but when I go to Dr. Eisner I'm happy to go. He is very professional and makes you feel comfortable because he always puts a smile on your face. Thank you Dr. Eisner for always making me smile, saving lives, and having me as your patient for all these years! You're the best doctor!!!!!

"Thankful for everything"

Since 2004, you have been there for me. You have helped me and kept me up to date with my exams! Thankful for everything. You are the best!

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