The ACI technique is designed to treat and repair cartilage defects by regenerating the patient’s own hyaline cartilage, a weight-bearing cartilage that lines the surface of the knee joint. Learn about Dr. Domby’s approach to the ACI technique below.

1. Knee Examined
Through a small incision in the knee, the surgeon uses an arthroscope to look for signs of damage in the
knee joint.

2. Sample Removed
If a defect is found, the surgeon removed a small sample of healthy cartilage from a non weight-bearing region of the knee.

3. Cells Cultured
The sample is sent to the Genzyme laboratory, where it is stimulated to produce approximately 12 million similar cells. The process, called cell culturing, takes about four to five weeks. Once completed, the new cells are returned to the surgeon.

4. Diseased Cartilage Removed
The surgeon now performs a second surgery to implant the new cartilage cells. First, the surgeon removes the knee’s damaged or diseased cartilage, along with any loose tissue.

5. Periosteum Removed
A small patch of thin, fibrous tissue called periosteum is removed from the surface of the tibia.

6. Patch Sewn
The periosteum patch is sewn over the area where the diseased or damaged cartilage was removed.

7. Cells Implanted
The cultured cells are implanted beneath the patch through a thin needle.

8. End of Procedure
Over time, the cultured cells will adhere to the damaged area, forming a new layer of weight-bearing
cartilage tissue.